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and 190-fold selective against Raf
29-28-11-4-3-9(8-16-11)18(22)23)6-5-13(20)27-17-12(19)7-10(14(17)21)30(24
InChiKey: YRFRBTOMOUXLRJ-UHFFFAOYSA-M
InChiKey: OOZYLOMMGMLDHT-BIVGDOEESA-N
FD223 (20 and 40 mg/kg
BSJ-04-132 l milnacipran-d5 and 190-fold selective against RafBSJ 04 132 is a potent and selective Ribociclib based CDK4 degrader (PROTAC), with IC50s of 50. 6 nM and 30 nM for CDK4 D1 and CDK6 D1, respectively. BSJ 04 132 does not induce CDK6 and IKZF1 3 degradation. BSJ 04 132 has anti cancer activity. Product information CAS Number: 2349356 39 2 Molecular Weight: 819. 91 Formula: C42H49N11O7 Chemical Name: 7 cyclopentyl 2 [(5 {4 [4 (2 {[2 (2,6 dioxopiperidin 3 yl) 1,3 dioxo 2,3 dihydro 1H isoindol 4
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