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CUDC-101 was used at 1 µM final concentration in vitro and in cellular assays
Preclinical studies have demonstrated that the compound promotes the function and survival of neurons and other cell types under disease-relevant stress conditions through interactions with the mitochondrial permeability transition pore (mPTP)
3)35-27-17-15-26(16-18-27)34-21-25-19-23-10-4-5-11-24(23)20-32(25)30(33)29-14-8-12-22-9-6-7-13-28(22)29/h4-18
3-difluoroazetidin-1-yl)prop-2-en-1-one
It shows potent cytotoxic and cytostatic effect in human leukemic cell lines
Duocarmycin MA Catalog No.:M12157-10 CUDC-101 was used at 1Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MA can be used against multi drug resistant cell lines. Product information CAS Number: 1613286 57 9 Molecular Weight: 611. 09 Formula: C34H31ClN4O5 Chemical Name: tert butyl N [4 ({2 [(1S) 1 (chloromethyl) 5 hydroxy 1H, 2H, 3H benzo[e]indole 3 carbonyl] 1H indol 6 yl}carbamoyl)phenyl]carbamate Smiles:
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