Bosutinib hydrate Size:Contact [email protected] for quotation Smiles: CC1=CC=CC=C1N1C(=O)C2=C(C=CC=C2C)N=C1CN1C=NC2=C(N)N=CN=C12

Smiles: CC1=CC=CC=C1N1C(=O)C2=C(C=CC=C2C)N=C1CN1C=NC2=C(N)N=CN=C12

592 out of a panel of 76 kinases)

Formula: C27H28N4O5S

InChiKey: WVJKUGVVYXCLFV-CCHMMTNSSA-N

TCS-OX2-29 is a potent

Bosutinib hydrate Size:Contact [email protected] for quotation Smiles: CC1=CC=CC=C1N1C(=O)C2=C(C=CC=C2C)N=C1CN1C=NC2=C(N)N=CN=C12Bosutinib, also known as SKI 606, is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. Unlike imatinib, bosutinib inhibits the autophosphorylation of both Abl and Src kinases, resulting in inhibition of cell growth and apoptosis. Because of the dual mechanism of action, this agent may have activity in resistant CML disease, other myeloid malignancies and solid