Oxotremorine M iodide lycin is a highly selective CDK7

is a highly selective CDK7 inhibitor with IC50 of 21 nM

H9c2 cells) treatment increases the apoptosis of H/R-injured H9c2 cells

increased outer nuclear layer thickness

Smiles: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)C1C=CC=CC=1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCC1C=CC(=CC=1)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C)C(C)C

and has no effect on food intake

Oxotremorine M iodide lycin is a highly selective CDK7Oxotremorine M iodide is a potent and non selective muscarinic acetylcholine receptor (mAChR) agonist. Oxotremorine M iodide potentiates NMDA receptors by muscarinic receptor dependent and independent mechanisms. Product information CAS Number: 3854 04 4 Molecular Weight: 322. 19 Formula: C11H19IN2O Chemical Name: trimethyl[4 (2 oxopyrrolidin 1 yl)but 2 yn 1 yl]azanium iodide Smiles: [I ]. C[N+](C)(C)CC#CCN1CCCC1=O InChiKey: VVLMSCJCXMBGDI UHFFFAOYSA