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InChi: InChI=1S/C12H10Br2N2/c13-7-9-3-1-5-11(15-9)12-6-2-4-10(8-14)16-12/h1-6H
Soticlestat (TAK-935
AMG-009 inhibits PGD2-induced down-modulation of CRTH2 on CD16 negative granulocytes (eosinophils) in human whole blood with a Ki of 1 nM
InChiKey: WVJKUGVVYXCLFV-CCHMMTNSSA-N
and TYR89) are key to the activation site of LYN-1604 and ULK1 by site-directed mutagenesis and biochemical assays
I-BET282E - CAS# 2885162-99-0 Catalog No.:M34971-C InChi: InChI=1S/C12H10Br2N2/c13-7-9-3-1-5-11(15-9)12-6-2-4-10(8-14)16-12/h1-6HI BET282E is a pan inhibitor of all eight BET bromodomains, and selectivity over other representative bromodomain containing proteins. I BET282E shows pIC50s ranging 6. 4 7. 7 for BRD2 (BD1 BD2), BRD2 (BD1 BD), BRD3 (BD1 BD), and BRD4 (BD1 BD). Product information CAS Number: 2885162 99 0 Molecular Weight: 546. 64 Formula: C26H34N4O7S Chemical Name: 4 {8 methoxy 1 [(2R) 1 methoxypropan 2 yl] 2 (oxan 4 yl) 1H imidazo[4,5 c]quinolin 7 yl} 3,5 dimethyl