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AMG-Tie2-1 (compound 15) inhibits Tie-2 phosphorylation in EA
InChiKey: XCIGZBVOUQVIPI-UHFFFAOYSA-N
SB-218078 (500-625 μM
2009 Aug 12
InChi: InChI=1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7
LP-184 490olCDE-IN-2 AMG-Tie2-1 (compound 15) inhibits Tie-2LP 184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP 184 has potent anti cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2). Product information CAS Number: 924835 67 6 Molecular Weight: 304. 34 Formula: C16H20N2O4 Chemical Name: 1 hydroxy 1 {[(6'R) 6' hydroxy 2',4',6' trimethyl 7' oxo 6',7' dihydrospiro[cyclopropane 1,5' inden] 3' yl]methyl}urea Smiles:
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