Epidermal Growth Factor Receptor Peptide (985-996) Catalog No.:M23036-C Smiles: CC1=CN([C@H]2C[C@H](O)[C@@H](COC(C3=CC=CC=C3)(C3=CC=C(C=C3)OC)C3=CC=C(C=C3)OC)O2)C(=O)N=C1NC(=O)C1=CC=CC=C1

Smiles: CC1=CN([C@H]2C[C@H](O)[C@@H](COC(C3=CC=CC=C3)(C3=CC=C(C=C3)OC)C3=CC=C(C=C3)OC)O2)C(=O)N=C1NC(=O)C1=CC=CC=C1

which inhibits calcium flux mediated by the receptors

Valenzuela CA

has a long half-life and tissue penetration

C4H4O4/c2*1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5

Epidermal Growth Factor Receptor Peptide (985-996) Catalog No.:M23036-C Smiles: CC1=CN([C@H]2C[C@H](O)[C@@H](COC(C3=CC=CC=C3)(C3=CC=C(C=C3)OC)C3=CC=C(C=C3)OC)O2)C(=O)N=C1NC(=O)C1=CC=CC=C1EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by the binding of its specific ligands, including epidermal growth factor and transforming growth factor . EGFR dimerization stimulates its intrinsic intracellular protein tyrosine kinase activity. As a result, autophosphorylation of several tyrosine (Y) residues on the C terminal domain of EGFR occurs. These include Y992, Y1045, Y1068, Y1148 and Y1173. This