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PubMed PMID: 21249704
InChiKey: PNYRDVBFYVDJJI-UHFFFAOYSA-N
Although its mechanism of action has yet to be fully elucidated
KN-62 is found to be a potent antagonist in a functional assay
Chemical Name: 5-Iodo-2-[[(2S)-1-oxo-3-phenyl-2-[(phenylmethyl)amino]propyl]amino]-benzoic acid
PMPA - CAS# 173039-10-6 Catalog No.:M6520-10 PubMed PMID: 21249704PMPA, CAS No. 173039 10 6, is a NAALADase inhibitor. PMPA increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock induced seizures in mice. Inhibition of NAALADase by 2 PMPA attenuates cocaine induced relapse in rats: a NAAG mGluR2 3 mediated mechanism. PMPA attenuates magnetic resonance BOLD signals in brain of anesthetized mice: evidence of a link between neuron NAAG release and
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