SB939 ties CAS Number: 934240-31-0

CAS Number: 934240-31-0

MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo

InChiKey: AFJRDFWMXUECEW-LBPRGKRZSA-N

and increased compliance

ZM-306416 is also found to inhibit the ABL in vitro kinase activity with a less potent IC50 value of 1

SB939 ties CAS Number: 934240-31-0SB939, is an orally bioavailable, small molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis.