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101(10):2207-13
9% in Bardoxolone methyl-treated monkeys[3]
Formula: C19H23NO8
33 mg/mL (228
) reverses Reserpine (HY-N0480) -induced akinesia in rats
Dasatinib monohydrate - CAS# 863127-77-9 isandrin C 101(10):2207-13Dasatinib (BMS 354825) monohydrate is a highly potent, ATP competitive, orally active dual Src Bcr Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr Abl, respectively. Dasatinib monohydrate inhibits Bcr Abl and Src with IC50s of <1. 0 nM and 0. 5 nM, respectively. Dasatinib monohydrate also induces apoptosis and autophagy. Product information CAS Number: 863127 77 9 Molecular Weight: 506. 02 Formula:
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