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Chemical Name: (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5
It blocks the proliferation of UACC-812 tumor cells expressing higher levels of JARDID1B
Print 2016 Apr
105628-72-6
Kleinhenz JM
NB-598 free base - CAS# 131060-14-5 Catalog No.:M7122-2 Chemical Name: (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5NB 598 free base, CAS No. 131060 14 5, is a potent competitive inhibitor of squalene epoxidase (SE). NB 598 suppresses triglyceride biosynthesis through the farnesol pathway. NB 598 suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. NB 598 reduced basolaterally secreted radioactivity in cholesterol, cholesterol ester, PL and TG. Furthermore, NB 598 suppressed the basolateral
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