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WO2014055647A1
4 nM for EGFRwt
Williams VC
InChi: InChI=1S/C38H44O8/c1-20(2)10-9-15-36(8)16-14-24-29(39)28-30(40)26-18-23-19-27-35(6
a novel anti-inflammatory drug
SKF-82958 hydrobromide 3885 WO2014055647A1SKF 82958 (() SKF 82958) hydrobromide is a dopamine D1 receptor full agonist (K0. 5=4 nM), displays selective for D1 over D2 receptors (K0. 5=73 nM). SKF 82958 hydrobromide induces dopamine D1 receptor dependent adenylate cyclase activity in rat striatal membranes (EC50=491 nM). Product information CAS Number: 74115 01 8 Molecular Weight: 410. 73 Formula: C19H21BrClNO2 Chemical Name: 6 chloro 1 phenyl 3 (prop 2 en 1 yl) 2,3,4,5 tetrahydro 1H 3