Indirubin-3'-monoxime-5-sulphonic acid Size:2mg solid A multigram chemical synthesis of

A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers

1-8H3/b13-12-

Chemical Name: (S)-2-((S)-2-(3

2013 Dec 7

At the 1 mg/kg dose CC-115 shows significant inhibition at 1 and 3 hours

Indirubin-3'-monoxime-5-sulphonic acid Size:2mg solid A multigram chemical synthesis ofIndirubin 3' monoxime 5 sulphonic acid is a potent and selective inhibitor of CDK1, CDK5, and GSK 3 with IC50s of 5 nM, 7 nM, and 80 nM, respectively. Product information CAS Number: 331467 05 1 Molecular Weight: 357. 34 Formula: C16H11N3O5S Chemical Name: (E, 3E) 3 (hydroxyimino) 2' oxo 1', 2' dihydro 1H, 3H [2, 3' biindolylidene] 5' sulfonic acid Smiles: O N=C1 C( NC2=CC=CC=C 12)=C1 C2=CC(=CC=C2NC 1=O)S(O)(=O)=O InChiKey: VUIXUTVIIOVVHV OIXOFKMYSA N