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20 µM inhibits the cell growth of both cell lines effectively in a time- and dose-dependent manner
Smiles: C1NN=C(C=1C1=CC=NC2=CC=CC=C21)C1=CC=CC=N1
InChi: InChI=1S/C20H17ClN4O3/c1-11-23-24-20-16(10-18(26)27)22-19(12-3-5-13(21)6-4-12)15-9-14(28-2)7-8-17(15)25(11)20/h3-9
Using the established scintillation proximity assay (SPA) assay
33)/t10-/m0/s1
N-(4-acetamidophenyl)-Indomethacin amide Catalog No.:M22631-C 20 µM inhibits the cellN (4 acetamidophenyl) Indomethacin amide is a reversible, potent and selective COX 2 inhibitor . Cyclooxygenase (COX) is an enzyme responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin. COX 1 is the constitutive isoform and is mainly responsible for the synthesis of cytoprotective prostaglandins in the gastrointestinal tract (GI) and of the proaggregatory thromboxane in blood platelets. COX 2 is