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Q-VD-OPh hydrate - CAS# 1135695-98-5 o-13-carotenone CAS Number: 945667-22-1

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Description

CAS Number: 945667-22-1

S1071-9164(19)31802-0

27)28)29-24(32)20-4-2-19(3-5-20)17-30-12-14-33-15-13-30/h2-7

C4H6O6/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18

PLK1 inhibition leads to pharmacodynamic pHisH3 modulation and significant antitumor activity in multiple DLBCL models

Q-VD-OPh hydrate - CAS# 1135695-98-5 o-13-carotenone CAS Number: 945667-22-1The broad spectrum caspase inhibitor, QVD OPh, provides a cost effective, non toxic, and highly specic means of apoptotic inhibition and provides new insight into the design of new inhibitors1. Actinomycin D rapidly induced apoptosis and this was dramatically inhibited by the caspase inhibitor, Q VD OPh (quinolyl valyl O methylaspartyl [ 2, 6 diuorophenoxy] methyl ketone). Q VD OPh was signicantly more effective in preventing apoptosis than the widely

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