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NLRP3-IN-NBC6 Size:Contact [email protected] for quotation InChi: InChI=1S/C8H16BrNO3/c1-2-10-8(11)7-13-6-5-12-4-3-9/h2-7H2

SKU: 79565587299

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Description

InChi: InChI=1S/C8H16BrNO3/c1-2-10-8(11)7-13-6-5-12-4-3-9/h2-7H2

InChiKey: CABBMMXFOOZVMS-PMERELPUSA-N

Smiles: OCNC(=O)C1C=CC=NC=1

a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers

KD5170 resulted in histone hyperacetylation with an EC50 of 25 nM in a concentration-dependent way

NLRP3-IN-NBC6 Size:Contact [email protected] for quotation InChi: InChI=1S/C8H16BrNO3/c1-2-10-8(11)7-13-6-5-12-4-3-9/h2-7H2NLRP3 IN NBC6 is a potent, selective NLRP3 inflammasome inhibitor (IC50= 574 nM) that acts independently of Ca2+. NLRP3 IN NBC6 inhibits Nigericin (HY 127019) induced inflammasome activation in THP 1 cells and Imiquimod (HY B0180) induced IL 1 release from LPS primed bone marrow derived macrophages (BMDMs). Product information CAS Number: 2068818 02 8 Molecular Weight: 409. 50 Formula: C18H16BCl3N2O2 Chemical Name: 5 acetyl 6 amino 2,2 diphenyl 4

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