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4-dinitro-6-(octan-2-yl)phenyl (2E)-but-2-enoate
MK-3697 is also the third insomnia drug
5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid
InChi: InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11
Smalley TL Jr
PP1 (Givinostat) 4-dinitro-6-(octan-2-yl)phenyl (2E)-but-2-enoatePP1 is a potent and selective Src family protein tyrosine kinase inhibitor. PP1 effectively blocks TGF beta1 induced cell migration and invasion in both established and primary carcinoma cells. PP1 blocks TGF beta1 mediated cellular responses by direct and differential inhibition of type I and type II TGF beta receptors. PP1 was also found to potentiate tumor suppressive effect of connexin 32 gene in renal cancer cells. Product information CAS Number:
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