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GSK1904529A HC 80267 2019 Aug 15

SKU: 78650932834

4.4
USD130.00 USD170.00

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Description

2019 Aug 15

CW-069 is an allosteric inhibitor of HSET with an IC50 of 75 μM

2005 Sep 1

Sobieszek G

irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity

GSK1904529A HC 80267 2019 Aug 15GSK 1904529A, also known as GSK 4529, is an IGF 1R Inhibitor, is is a promising candidate for therapeutic use in IGF IRdependent tumors. GSK1904529A selectively inhibits IGF IR and IR with IC50s of 27 and 25 nmol L, respectively. GSK1904529A blocks receptor autophosphorylation and downstream signaling, leading to cell cycle arrest. It inhibits the proliferation of cell lines derived from solid and hematologic malignancies, with multiple myeloma and

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