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Radotinib Catalog No.:M10972-2 6R)-4-methoxy-16

SKU: 77702569761

4.5
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Description

6R)-4-methoxy-16

can be nitrated directly

In MMTV-Wnt1 tumor models

Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase

PMID: 18423777

Radotinib Catalog No.:M10972-2 6R)-4-methoxy-16Radotinib, also known as IY 5511, is an orally available, a second generation tyrosine kinase inhibitor of Bcr Abl fusion protein and the platelet derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR

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