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6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-[[trans-4-(dimethylamino)cyclohexyl]ethylamino]-2-methylbenzamide
CAS Number: 651729-53-2
Formula: C6H14Cl2N4O2
21-54-44)28(47)18-42(41
CAS Number: 105816-04-4
ATR inhibitor 2 oxamide Tromethamine 6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-[[trans-4-(dimethylamino)cyclohexyl]ethylamino]-2-methylbenzamideATR inhibitor 2 is an ATP competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. ATR inhibitor 2 potently inhibits ATR driven phosphorylated checkpoint kinase 1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity. Product information CAS Number: 1613191 99 3 Molecular Weight: 541. 55 Formula: C25H29F2N9O3 Chemical Name: 2 amino 6 fluoro N (5 fluoro 4 {4 [4 (oxetan 3 yl)piperazine 1 carbonyl]piperidin 1 yl}pyridin 3