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Also displays activity against PKA and CDK2 with IC50 values of 16nM and 46nM respectively
The inhibitor is significantly less active towards other kinases
Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity
Chemical Name: 4-[(8-Aminooctyl)oxy]-2-(2
Delphinidin chloride shows endothelium-dependent vasorelaxation
PD-089828 camsule.2Na Also displays activity against PKAPD 089828 is an ATP competitive inhibitor of FGFR 1, PDGFR and EGFR (IC50s=0. 15, 1. 76, and 5. 47 M, respectively) and a noncompetitive inhibitor of c Src tyrosine kinase (IC50=0. 18 M). PD 089828 also inhibits MAPK with an IC50 of 7. 1 M. PD 089828 inhibits PDGF , EGF and bFGF mediated tyrosine kinase receptor autophosphorylation in vitro. PD 089828 has a long lasting cellular activity. Product information CAS Number: 179343 17 0 Molecular Weight:
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