Chemical Name: 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide
This agent functions as an estrogen agonist in some tissues (bones
which was involved in stemness of CSC
InChi: InChI=1S/C17H16F6N2O
CCT251545 potently inhibits WNT pathway activity in COLO205-F1756 clone 4 (an APC -mutant human colorectal cancer cell line engineered to express a modified luciferase-based WNT reporter construct) with an IC50 of 0
Isosilybin A - CAS# 142796-21-2 inib Hydrochloride Chemical Name: 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamideIsosilybin A, a flavonolignan isolated from silymarin, has anti prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt NF B androgen receptor (AR) axis. Product information CAS Number: 142796 21 2 Molecular Weight: 482. 44 Formula: C25H22O10 Chemical Name: (2R, 3R) 3, 5, 7 trihydroxy 2 [(2R, 3R) 2 (4 hydroxy 3