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APX-115 might be a promising therapeutic agent for the treatment of DN because of its pan-NOX inhibitory activity
Passacantilli S
acting via the HIF-1α system
GSK256066 is a slow and tight binding inhibitor of PDE4B with apparent IC50 of 3
Lisabeth EM
Clinafloxacin 0201 APX-115 might be a promisingClinafloxacin (free base) is an investigational fluoroquinolone antibiotic. Despite its promising antibiotic activity, the clinical development of clinafloxacin has been hampered by its risk for inducing serious side effects. Product information CAS Number: 105956 97 6 Molecular Weight: 365. 79 Formula: C17H17ClFN3O3 Synonym: PD127391 PD 127391 PD 127391 AM 1091 CI 960 Chemical Name: 7 (3 aminopyrrolidin 1 yl) 8 chloro 1 cyclopropyl 6 fluoro 4 oxo 1,4