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NSC-253272
CAS Number: 1357072-61-7
p-Synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine
IGF-1R and PDGFRβ in A431 cells
InChiKey: DUWPGRAKHMEPCM-IZZDOVSWSA-N
TAK-960 dihydrochloride 31156 NSC-253272TAK 960 dihydrochloride is an orally available, selective inhibitor of polo like kinase 1 (PLK1), with an IC50 of 0. 8 nM. TAK 960 dihydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16. 9 and 50. 2 nM, respectively. TAK 960 dihydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts. Product information Molecular Weight: 634. 52 Formula: