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6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3
Yongseok Choi
3-dihydroxypropyl phosphonato]oxy}ethyl)trimethylazanium
Rucaparib (AG014699) is an orally active and potent inhibitor of PARP with Ki of 1
3-weekly i
Nepicastat Size:Solid 10 mg 6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3Nepicastat, also known as SYN117 and RS 25560 197, is an inhibitor of dopamine beta hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. It has been studied as a possible treatment for congestive heart failure, and appears to be well tolerated. As of 2012, clinical trials to assess nepicastat as a treatment for post traumatic stress disorder (PTSD) and cocaine dependence have been completed. In Phase 2 study treatment