-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2R](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M10296_1621561651.gif?v=1742877632)
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3-bis(hexadecanoyloxy)propoxy]({2-[(2S)-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2R
but not CCR5−
CAS Number: 1240299-33-5
88(4):309-20
In primary human bronchial epithelial (HBE) cells with F508del-CFTR mutation
NVP-BKM120 Hydrochloride - CAS# 1312445-63-8 Catalog No.:M10296-2 3-bis(hexadecanoyloxy)propoxy]({2-[(2S)-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2RBuparlisib, also known as BKM120, is an orally bioavailable specific oral inhibitor of the pan class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases with potential antineoplastic activity. PI3K inhibitor BKM120 specifically inhibits class I PIK3 in the PI3K AKT kinase (or protein kinase B) signaling pathway in an ATP competitive manner, thereby inhibiting the production of the secondary messenger phosphatidylinositol 3,4,5 trisphosphate
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