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It is marketed as Serevent in the US
2-48 hours) induces apoptosis in 2F7 cells
35 mcg/mL)
2 µM concentration in cellular assays to investigate its effects on the PI3K/AKT signaling pathways
500 nM) also causes ER stress machinery and mitochondrial damage in WM cells
Lesinurad - CAS# 878672-00-5 OH000 It is marketed as SereventLesinurad, also known as RDEA594, is a selective uric acid re absorption inhibitor (SURI) and is also a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. RDEA594 has been shown to normalize the amount of uric acid excreted by gout patients previously classified as under excretors. Lesinurad received FDA approval on December 22, 2015. Product information CAS Number: 878672 00 5 Molecular Weight: