Almotriptan Malate Catalog No.:M9101-2 CAS Number: 182004-65-5

CAS Number: 182004-65-5

InChiKey: YSTVFDAKLDMYCR-NDEPHWFRSA-N

Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF- and basicfibroblast growth factor-induced angiogenesis in vivo and in vitro

Strotman NA

In vitro metabolite identification studies in hepatocytes revealed predominant formation of an inactive metabolite (M1) via amide hydrolysis in human

Almotriptan Malate Catalog No.:M9101-2 CAS Number: 182004-65-5Almotriptan Malate is a triptan drug discovered and developed by Almirall for the treatment of heavy migraine headache. Almotriptan is a Serotonin 1b and Serotonin 1d Receptor Agonist. Binding of the drug to the receptor leads to vasoconstriction of the cranial blood vessels and thus affects the redistribution of cranial blood flow. Almotriptan significantly increases cerebral blood flow and reduces blood flow through extracerebral cranial vessels.