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2014 Jan 23
dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide
indoleacetic acid
5-24 hours) induces about a five-fold upregulation of Nur77 mRNA expression in hEP2-HEK293/EBNA cells in a dose- and time-dependent
and has at least 500-fold higher selectivity to ErbB2 than EGFR
LMT-28 ycyrrhetinic acid 2014 Jan 23LMT 28 is an orally active and the first synthetic IL 6 inhibitor that functions through direct binding to gp130. LMT 28 shows low toxicity and selectively inhibits IL 6 induced phosphorylation of STAT3, JAK2, and gp130. Product information CAS Number: 1239600 18 0 Molecular Weight: 311. 42 Formula: C17H29NO4 Chemical Name: (4S) 3 [(2S,3S) 3 hydroxy 2 methyl 4 methylidenenonanoyl] 4 (propan 2 yl) 1,3 oxazolidin 2 one Smiles: