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Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C 2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl)methyl]-4-azatricyclo[5

SKU: 70165967152

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Description

2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl)methyl]-4-azatricyclo[5

a novel JAK2 inhibitor

InChi: InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H

CAS Number: 555-66-8

6 and 1 μM respectively

Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C 2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl)methyl]-4-azatricyclo[5Dual PARP EGFR ligand for PROTAC incorporates a ligand for PARP and EGFR , and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). Dual PARP EGFR ligand for PROTAC can be used in the synthesis of DP C 4, which is CRBN based dual PROTAC for simultaneous degradation of EGFR and PARP. Product information Molecular Weight: 1020. 52 Formula: C53H56ClF2N9O8 Chemical Name: 6 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6

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