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CAS Number: 139886-04-7
3, 5-Diiodothyropropionic Acid 5209 CAS Number: 139886-04-73,5 Diiodothyropropionic acid (DITPA) is an inotropic thyroid hormone analogue of L thyroxine that binds to the thyroid hormone receptors TR and TR (Kas = 2. 4 and 4. 06 x 107 M 1, respectively, for human recombinant receptors). 1 DITPA increases mRNA expression of myosin heavy chain ( MHC) in primary rat cardiomyocytes (EC50 = ~0. 5 M). Ex vivo, DITPA prevents myocardial infarction induced loss of contractility in rabbit cardiomyocytes when
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