SC75741 L-arabinoside Smiles: C[C@H]1O[C@@H]2[C@@H](CO1)O[C@@H](O[C@H]1[C@H]3COC(=O)[C@@H]3[C@@H](C3=CC4OCOC=4C=C31)C1=CC(OC)=C(O)C(=C1)OC)[C@H](O)[C@H]2O

Smiles: C[C@H]1O[C@@H]2[C@@H](CO1)O[C@@H](O[C@H]1[C@H]3COC(=O)[C@@H]3[C@@H](C3=CC4OCOC=4C=C31)C1=CC(OC)=C(O)C(=C1)OC)[C@H](O)[C@H]2O

11aS)-1-hydroxy-9a

5 μM and 0

5-dimethyl-1H-pyrrol-1-ide difluoride

10-trien-4-imine

SC75741 L-arabinoside Smiles: C[C@H]1O[C@@H]2[C@@H](CO1)O[C@@H](O[C@H]1[C@H]3COC(=O)[C@@H]3[C@@H](C3=CC4OCOC=4C=C31)C1=CC(OC)=C(O)C(=C1)OC)[C@H](O)[C@H]2OSC75741 is a broad and efficient NF B inhibitor with an IC50 of 200 nM for p65. SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF B subunit p65, resulting in reduced expression of cytokines, chemokines, and pro apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase mediated nuclear export of viral ribonucleoproteins. Product information CAS Number: 913822 46 5 Molecular Weight: