Eltanexor (KPT-8602) Size:Contact [email protected] for quotation JAK2 and JAK3 with IC50

JAK2 and JAK3 with IC50 of 0

2017 Jul 25

CAS Number: 1351522-04-7

and cholesterol homoeostasis

added at 15 and 30 µM

Eltanexor (KPT-8602) Size:Contact [email protected] for quotation JAK2 and JAK3 with IC50Eltanexor, also known as KPT 8602, is a second generation exportin 1 inhibitor. KPT 8602 demonstrates potent activity against acute lymphoblastic leukemia. KPT 8602 is well tolerated and highly active against AML blasts and leukemia initiating cells. Eltanexor shows improved efficacy and in vivo tolerability in hematological malignancies. KPT 8602 is a potent inhibitor of AML cells in cell based viability assays. KPT 8602 inhibits XPO1 cargo