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AMG-Tie2-1 622C-1215 Smiles: COC1=NC=CN=C1NS(=O)(=O)C1=CC=CC(Cl)=C1Cl

SKU: 68979027181

4.1
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Description

Smiles: COC1=NC=CN=C1NS(=O)(=O)C1=CC=CC(Cl)=C1Cl

added at 15 and 30 µM

2)10-8-17(15)20/h13-18

Chemical Name: (2E)-3-{4-[(1H-imidazol-1-yl)methyl]phenyl}prop-2-enoic acid

and bicuculline-induced seizures and 6-Hz “psychomotor” seizures with median effective dose (ED50) values of 151

AMG-Tie2-1 622C-1215 Smiles: COC1=NC=CN=C1NS(=O)(=O)C1=CC=CC(Cl)=C1ClAMG Tie2 1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) with an IC50 of 1 nM. AMG Tie2 1 is a VEGFR2 inhibitor with an IC50 of 3 nM. Product information CAS Number: 870223 96 4 Molecular Weight: 479. 45 Formula: C25H20F3N5O2 Chemical Name: 4 methyl 3 ({3 [2 (methylamino)pyrimidin 4 yl]pyridin 2 yl}oxy) N [3 (trifluoromethyl)phenyl]benzamide Smiles: CC1=CC=C(C=C1OC1=NC=CC=C1C1=CC=NC(NC)=N1)C(=O)NC1=CC(=CC=C1)C(F)(F)F InChiKey:

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