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PMID: 32059151
Chemical Name: (2S)-5-hydroxy-2-(4-methoxyphenyl)-7-{[(2S
WDR5-C47 could serve as a tool compound to study functions of SET1-family of human histone methyltransferases and further develop therapeutic drug molecules targeting the WDR5−MLL interaction
2ClH/c1-14(19(26(3)4)16-10-6-5-7-11-16)22-20-17-12-8-9-13-18(17)21-24-23-15(2)27(21)25-20
CAS Number: 1184136-10-4
AG-82 p2m myristoylated TFA PMID: 32059151AG 82 is a cell permeable, reversible, and competitive inhibitor of tyrosine kinase and epidermal growth factor (EGF) receptor. Protein tyrosine kinases (PTKs) have been involved in regulating cell proliferation, cell differentiation, and signaling processes in the immune system. Dysfunction of protein tyrosine kinases result in inflammatory responses and diseases including cancer, atherosclerosis, and psoriasis . The epidermal growth factor receptor
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