SJF 1521 - EGFR Degrader. CAS# 2230821-40-4 size:2mg solid Smiles: CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=C(NCCC3=CC=C(CCC(O)=O)C=C3)N=C12

Smiles: CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=C(NCCC3=CC=C(CCC(O)=O)C=C3)N=C12

In the murine aortic allograft model

286(25):22570-9

OG-L002 suppressed primary lytic infection of HSV in vivo in a mouse model

Smiles: COCCN(C)C1C=CC(=CC=1)NC(=O)C1N=C(OC=1C(F)(F)F)C1C=CC=CC=1

SJF 1521 - EGFR Degrader. CAS# 2230821-40-4 size:2mg solid Smiles: CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=C(NCCC3=CC=C(CCC(O)=O)C=C3)N=C12SJF 1521, EGFR Degrader, CAS No. 2230821 40 4, is a selective EGFR Degrader. It induces degradation of EGFR in OVCAR8 cells. Product information CAS Number: 2230821 40 4 Molecular Weight: 1074. 65 Formula: C57H61ClFN7O9S Synonym: SJF 1521 SJF1521 Chemical Name: (2S,4R) 1 ((S) 2 (tert butyl) 14 (4 (4 ((3 chloro 4 ((3 fluorobenzyl)oxy)phenyl)amino)quinazolin 6 yl)phenoxy) 4 oxo 6,9,12 trioxa 3 azatetradecanoyl) 4 hydroxy N (4 (4 methylthiazol 5