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NB-598 Hydrochloride alafenamide hemifumarate Solubility: DMSO: 100 mg/mL(134

SKU: 66787174491

4.1
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Description

Solubility: DMSO: 100 mg/mL(134

Smiles: O=C(NC1=NC=C(CCNC2=NC=NC3C=CSC=32)S1)NC1=CC(Cl)=CC=C1

2-dimethylpropanoyl)oxy]benzenesulfonamido}phenyl)formamido]acetic acid sodium

Chemical Name: N-[(2S)-1-amino-3-(3

The induction of angiogenesis by bFGF is significantly inhibited by oral treatment of Lenalidomide in a dose-dependent manner

NB-598 Hydrochloride alafenamide hemifumarate Solubility: DMSO: 100 mg/mL(134NB 598 is a potent competitive inhibitor of squalene epoxidase (SE). NB 598 suppresses triglyceride biosynthesis through the farnesol pathway. NB 598 suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. NB 598 reduced basolaterally secreted radioactivity in cholesterol, cholesterol ester, PL and TG. Furthermore, NB 598 suppressed the basolateral secretion of apolipoprotein (apo) B.

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