TAK-683 TFA Catalog No.:M17751-C 4-dimethylpiperazin-1-yl]-6-methoxypyridin-2-yl}amino)pyrimidin-4-yl]benzonitrile

4-dimethylpiperazin-1-yl]-6-methoxypyridin-2-yl}amino)pyrimidin-4-yl]benzonitrile

Formula: C32H43N5O2

Gamma-glutamylcysteine TFA attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes

Galantamine Hydrobromide is the hydrobromide salt form of galantamine

ClH/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6

TAK-683 TFA Catalog No.:M17751-C 4-dimethylpiperazin-1-yl]-6-methoxypyridin-2-yl}amino)pyrimidin-4-yl]benzonitrileTAK 683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK 683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0. 96 nM and 1. 6 nM for human and rat, respectively. TAK 683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone dependent prostate cancer.