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AS-99 is used for in vivo studies in mice
2018 Aug 15
is a potent and selective inhibitor of IDH2 R140Q and R172K mutant first reported in patent WO 2013102431
InChi: InChI=1S/C21H21FN6/c1-13-20(22)16(7-18-21(13)25-12-28(18)9-14-3-4-14)26-19-6-5-15(8-23-19)17-10-27(2)11-24-17/h5-8
Formula: C20H23ClN2O4
Bosutinib D8 14306 AS-99 is used for inBosutinib D8 (SKI 606 D8) is a deuterium labeled Bosutinib. Bosutinib is a dual Src Abl inhibitor with IC50s of 1. 2 nM and 1 nM, respectively. Product information Molecular Weight: 538. 50 Formula: C26H29Cl2N5O3 Chemical Name: 4 ((2, 4 dichloro 5 methoxyphenyl)amino) 6 methoxy 7 (3 (4 methylpiperazin 1 yl 2, 2, 3, 3, 5, 5, 6, 6 d8)propoxy)quinoline 3 carbonitrile Smiles:
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