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5-²H₉)pentanamido)butanoic acid
maximal heart rate increases of 25 bpm
SI-2 causes minimal acute cardiotoxicity based on a hERG channel blocking assay and an unappreciable chronic toxicity to major organs based on histological analyses
Smiles: CC1N=CSC=1C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1
CAS Number: 903564-48-7
DBCO-PEG4-Ahx-DM1 PEG4)-L-Lysine-PFP ester 5-²H₉)pentanamido)butanoic acidDBCO PEG4 Ahx DM1 is a drug linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO PEG4 Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor specific delivery. Product information Molecular Weight: 1297. 92 Formula: C68H89ClN6O17 Chemical Name: [(2R,
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