Fluxametamide 92 dihydrochloride Smiles: CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@@H](CCSC)C(N)=O

Smiles: CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@@H](CCSC)C(N)=O

CHIR-090 at low nM levels inhibits LpxC orthologues from diverse Gram-negative pathogens

CAS Number: 102841-42-9

In cells with wild-type p53

Formula: C9H11F2N3O4

Fluxametamide 92 dihydrochloride Smiles: CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@@H](CCSC)C(N)=OFluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA and glutamate gated chloride channels, with IC50 of 1. 95 nM and 225 nM for M. domestica GABACls and GluCls. Product information CAS Number: 928783 29 3 Molecular Weight: 474. 26 Formula: C20H16Cl2F3N3O3 Chemical Name: 4 [5 (3,5 dichlorophenyl) 5 (trifluoromethyl) 4,5 dihydro 1,2 oxazol 3 yl] N [(1E) (methoxyimino)methyl] 2 methylbenzamide Smiles: CC1C=C(C=CC=1C(=O)N C=N