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54 nM for the inhibition of survivin promoter activity
Formula: C32H46N4O6S
dBET6 features highly increased cellular potency with evident degradation in the sub-nanomolar range
Also suitable for conventional confocal microscopy and live cell imaging
2) with lower affinity
ABT-492 Size:2mg solid 54 nM for the inhibitionABT 492 is a non zwitterionic fluoroquinolone antibiotic under development for for the treatment of respiratory and skin infections. Delafloxacin demonstrates excellent antibacterial potency and exhibits a low probability for the selection of resistant mutants in MRSA. Although mutants can be selected at low frequencies in vitro from quinolone resistant isolates, delafloxacin MICs and MPCs remain low and a fitness cost can be observed. Consequently
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