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Chemical Name: 1-(triphenylmethyl)-1H-imidazol-4-amine
Nutlin-3 treatment at 10 μM for 48 hours significantly induces caspase-dependent cell apoptosis by ~45%
Pomalidomide 4'-PEG4-azide is a functionalized cereblon ligand for PROTAC® research and development
Smiles: C[C@@](O)([C@@H](CC1C=CC(Cl)=CC=1)N1C=NC=N1)C1C=CC=CC=1
3)7-5(8(13)12-16-7)4-6(11)9(14)15/h6H
3-chloro-5-hydroxy BA Size:Contact [email protected] for quotation Chemical Name: 1-(triphenylmethyl)-1H-imidazol-4-amine3 chloro 5 hydroxy BA is a GPR81 agonist. GPR81 (HCA1) is a member of G protein coupled receptors (GPCRs). GPR81 is predominantly expressed on adipocytes and is activated by the endogenous ligands 2 hydroxypropanoate (lactate). Stimulation of GPR81 in adipose tissue lead to a decrease in the lipolysis of triglycerides by hormone sensitive lipase, which resulted in reduced transport of fatty acids to the liver and a decrease in hepatic triglycerides .