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PSN-GK1 60260 125(2):284-95

SKU: 63922959064

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Description

125(2):284-95

4-difluoro-N-{2-methoxy-5-[4-(pyridazin-4-yl)quinolin-6-yl]pyridin-3-yl}benzene-1-sulfonamide

PubMed PMID: 19300612

AP 26113-analog

highly selective and orally available ATR inhibitor BAY 1895344 with favorable PK properties and promising efficacy in monotherapy and combination in preclinical tumor models

PSN-GK1 60260 125(2):284-95PSN GK1 is a potent glucokinase activator with an EC50 of 0. 13 M. Product information CAS Number: 745051 61 0 Molecular Weight: 438. 54 Formula: C20H23FN2O4S2 Chemical Name: (2R) 2 [4 (cyclopropanesulfonyl)phenyl] N (5 fluoro 1,3 thiazol 2 yl) 3 (oxan 4 yl)propanamide Smiles: O=C(NC1=NC=C(F)S1)[C@H](CC1CCOCC1)C1=CC=C(C=C1)S(=O)(=O)C1CC1 InChiKey: DBMFNEZMJWKKPU QGZVFWFLSA N InChi: InChI=1S C20H23FN2O4S2 c21 18 12 22 20(28 18)23 19(24)17(11 13 7 9 27

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