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ZLN005 - PGC-1α Transcriptional Activator. CAS# 49671-76-3 size:10mg solid 21-11+/t26-/m0/s1

SKU: 63449016479

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Description

21-11+/t26-/m0/s1

It strongly reduces the proliferation and cell viability of T-ALL cell lines

The inhibitory activity of WZB117 on cancer cell growth is also confirmed with a clonogenic assay

CCG-267830

Chemical Name: (5-bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone

ZLN005 - PGC-1α Transcriptional Activator. CAS# 49671-76-3 size:10mg solid 21-11+/t26-/m0/s1ZLN005, CAS No. 49671 76 3, is a potent and selective small molecule PGC 1 transcriptional activator. It stimulates the expression of PGC 1 and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation. Chronic oral administration of ZLN005 at 15 mg kg per day to diabetic db db mice increased PGC 1 and downstream gene transcription in skeletal muscle, increasing fat oxidation and improving glucose tolerance,

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