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11aS)-1-ethynyl-1-hydroxy-11a-methyl-1H
BRD9757 was suggested to be used at 10 µM final concentration in vitro and in cellular assays
Formula: C42H62O16
143621-35-6
CAS Number: 456-12-2
OT-R antagonist 1 798rterolane 11aS)-1-ethynyl-1-hydroxy-11a-methyl-1HOT R antagonist 1 is a new potent and selective nonpeptide low molecular weight OT R antagonist. OT R antagonist 1 inhibits oxytocin evoked intracellular Ca2+ mobilization (IC50 = 8 nM). IC50 value: 8 nMTarget: oxytocin receptorin vitro: OT R antagonist 1 inhibitis IP3 Synthesis, rat OT R (IC50=0. 03 uM). OT R antagonist 1 inhibits phosphodiesterase IV with IC50 = 6. 1 M, a value about 300 fold higher than the affinity for OT R. OT R antagonist 1
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