K-Ras G12C-IN-3 Size:Solid 2 mg 119139-23-0

119139-23-0

5-h]isochromen-11-yl acetate

is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM)

3a]isobenzofuro[5

Ishikawa J

K-Ras G12C-IN-3 Size:Solid 2 mg 119139-23-0K Ras G12C IN 3 is a novel and irreversible inhibitor of mutant K ras G12C. IC50 value: Target: K ras G12C inhibitorFor more information, please see the following patent. Heterocyclic compounds as covalent inhibitors of G12C mutant K Ras protein useful for treating cancers, and preparation thereofBy Ren, Pingda; Liu, Yi; Li, Liansheng; Feng, Jun; Wu, Tao From PCT Int. Appl. (2014), WO 2014152588 A1 20140925. Product information CAS Number: 1629268 19