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SIRT-IN-3 Catalog No.:M28189-C Chemical Name: N-({3'-methanesulfonyl-[1

SKU: 61813728454

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Description

Chemical Name: N-({3'-methanesulfonyl-[1

InChiKey: WPYWMXNXEZFMAK-UHFFFAOYSA-N

Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain

CRT0066101 given orally (80 mg/kg/day) for 21 days in Panc-1 orthotopic model potently blocks tumor growth in vivo

PubMed PMID: 27756752

SIRT-IN-3 Catalog No.:M28189-C Chemical Name: N-({3'-methanesulfonyl-[1SIRT IN 3 is a potent SIRT inhibitor, with an IC50 of 17 M for SIRT1. SIRT IN 3 shows about 4 fold and 14 fold selectivity for SIRT1 over SIRT2 and SIRT3, respectively (IC50 of 74 M and 235 M for SIRT2 and SIRT3, respectively). Product information CAS Number: 1211 19 4 Molecular Weight: 212. 25 Formula: C13H12N2O Chemical Name: 2 (phenylamino)benzamide Smiles: NC(=O)C1=CC=CC=C1NC1C=CC=CC=1 InChiKey: JKWQUMKCVDUICQ UHFFFAOYSA N InChi: InChI=1S

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