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and induction of DNA damage
and this activation confers a high degree of selectivity of the drugs
4-dichlorophenoxy)methyl]-2-fluoro-N-methanesulfonylbenzamide
Nancarrow DJ
InChi: InChI=1S/C17H8Cl3N3O2/c18-8-1-3-10(13(20)5-8)15(24)12(7-21)16-22-14-6-9(19)2-4-11(14)17(25)23-16/h1-6
Palonosetron Hydrochloride llotoxin and induction of DNA damagePalonosetron (INN, trade name Aloxi) is a 5 HT3 antagonist used in the prevention and treatment of chemotherapy induced nausea and vomiting (CINV). It is used for the control of delayed CINVnausea and vomiting and there are tentative data to suggest that it may be better than granisetron. Palonosetron is administered intravenously, as a single dose, 30 minutes before chemotherapy, or as a single oral capsule one hour before chemotherapy. The oral