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GAK inhibitor 49 Size:Contact [email protected] for quotation InChi: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7

SKU: 60024608190

4.1
USD100.00 USD121.00

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Description

InChi: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7

3S)-2-[[(2S)-2-[[(2S)-1-[(2S

Smiles: CC1=NC=CC=C1C(=O)NC1C2NC3=CN=CC=C3C=2C=C(Cl)C=1OC

SU6668 (5-15 min) inhibits Flk-1 trans-phosphorylation (Ki=2

where as a higher dose combination of ABT-239 (3 mg/kg

GAK inhibitor 49 Size:Contact [email protected] for quotation InChi: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7GAK inhibitor 49 is a potent, ATP competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0. 54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 also shows binding to RIPK2. Product information CAS Number: 319492 82 5 Molecular Weight: 370. 40 Formula: C20H22N2O5 Chemical Name: 6,7 dimethoxy N (3,4,5 trimethoxyphenyl)quinolin 4 amine Smiles: COC1=CC2=C(C=CN=C2C=C1OC)NC1C=C(OC)C(OC)=C(C=1)OC InChiKey: VYPGLYMWNDRFGZ

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